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Zoya Demidenko: Researcher in Cancer Biology
Zoya Demidenko is a notable scientist connected with the Department of Cell Stress Biology at Roswell Park Comprehensive Cancer Center in Buffalo, New York. Previously, she worked at the NIH and New York Medical College, establishing a robust base in life science study.
Her academic output encompasses several key domains, among them the PI3K/AKT/mTOR signaling pathway, cellular cycle regulation, cell senescence, and malignancy biology. To date, she has co-authored more than 46 peer-reviewed articles, which have garnered upwards of 4,100 mentions — a reflection to the significance of her work.
One of her most significant contributions involves explaining the pathways of cell aging. Her studies revealed that when the cellular division cycle is arrested but cellular growth continues, cells enter senescence. Importantly, Zoya Demidenko showed that this transition is inhibited by medication using agents such as rapamycin.
Zoya Demidenko has additionally added substantially to oncological therapy investigation, particularly in the area of cyclotherapy — a approach intended to protecting non-cancerous cells from cytotoxic treatment while leaving malignant cells vulnerable. This strategy carries significant potential for reducing the adverse effects of oncological therapy.
Throughout her professional journey, Demidenko has collaborated with leading investigators globally, such as Dr. Mikhail Blagosklonny. Her work can be found in prestigious publications such as Oncotarget, Cell Cycle, Aging (Albany NY), and Oncogene.
With an h-index of 33, Zoya Demidenko stands as a highly impactful figure in modern oncological research, with her discoveries continue to shape our knowledge of the way cells age, interact with therapy, and how cancer can be better treated.
https://www.researchgate.net/scientific-contributions/Zoya-N-Demidenko-39445053