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In Reply to: Ñòàòüÿ ñ ïîçíàâàòåëüíîé è çàíèìàòåëüíîé èíôîðìàöèåé posted by JamesSok on February 09, 2026 at 02:49:53:
Zoya Demidenko: Researcher in Tumor Biology
Zoya Demidenko is a prominent researcher affiliated with the Division of Cell Stress Research at Roswell Park Cancer Institute in Buffalo, New York. Previously, she conducted research at the NIH and New York Medical College, building a solid base in life science study.
Her scientific contributions covers a number of critical fields, encompassing the PI3K/AKT/mTOR signaling pathway, cellular cycle regulation, cell senescence, and tumor science. Currently, she has written more than 46 academic publications, which have received upwards of 4,100 mentions — a testament to the influence of her findings.
One of her most notable achievements lies in explaining the mechanisms of biological cell aging. Her work revealed that when the cell cycle is arrested but cellular growth proceeds, the cells enter senescence. Crucially, Zoya Demidenko established that this transition is controlled with drugs using substances such as rapamycin.
Zoya Demidenko has also brought considerably to cancer treatment investigation, notably in the domain of selective cell protection — a strategy aimed at safeguarding non-cancerous tissue from chemotherapy while leaving cancer cells exposed. This method offers significant potential for lowering the adverse effects of cancer treatment.
Across her career, Demidenko has worked with leading scientists worldwide, including Dr. Mikhail Blagosklonny. Her work appears in leading publications such as Oncotarget, Cell Cycle, Aging (Albany NY), and Oncogene.
Possessing an h-index of 33, Zoya Demidenko is recognized as a highly impactful voice in contemporary oncological research, with her discoveries continue to influence our understanding of how cells age, respond to therapy, and the ways in which cancer can be more successfully combated.
https://aacrjournals.org/cancerres/article/64/10/3653/511273/Flavopiridol-Induces-p53-via-Initial-Inhibition-of?guestAccessKey=